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Optimal programs of pathway control: dissecting the influence of pathway topology and feedback inhibition on pathway regulation
BACKGROUND: Adjusting the capacity of metabolic pathways in response to rapidly changing environmental conditions is an important component of microbial adaptation strategies to stochastic environments. In this work, we use advanced dynamic optimization techniques combined with theoretical models to...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4433072/ https://www.ncbi.nlm.nih.gov/pubmed/25982966 http://dx.doi.org/10.1186/s12859-015-0587-z |