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Anti-CD28 Antibody-Initiated Cytokine Storm in Canines

CD28 signal blockade after T cell receptor activation is under intense investigation as a tolerance-inducing therapy for transplantation. Our goal is to produce a CD28-specific reagent as a therapy for the prevention of graft rejection and graft-versus-host disease in the canine model of allogeneic...

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Detalles Bibliográficos
Autores principales: Rosinski, Steven L., Storb, Rainer, Strong, Roland K., Sale, George E., Stone, Diane M., Gewe, Mesfin M., Friend, Della J., Abrams, V. Kraig, Randolph-Habecker, Julie, Graves, Scott S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4433175/
https://www.ncbi.nlm.nih.gov/pubmed/25988188
http://dx.doi.org/10.1097/TXD.0000000000000516