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Anti-CD28 Antibody-Initiated Cytokine Storm in Canines
CD28 signal blockade after T cell receptor activation is under intense investigation as a tolerance-inducing therapy for transplantation. Our goal is to produce a CD28-specific reagent as a therapy for the prevention of graft rejection and graft-versus-host disease in the canine model of allogeneic...
Autores principales: | Rosinski, Steven L., Storb, Rainer, Strong, Roland K., Sale, George E., Stone, Diane M., Gewe, Mesfin M., Friend, Della J., Abrams, V. Kraig, Randolph-Habecker, Julie, Graves, Scott S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4433175/ https://www.ncbi.nlm.nih.gov/pubmed/25988188 http://dx.doi.org/10.1097/TXD.0000000000000516 |
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