A Rare Co-Segregation-Mutation in the Insulin Receptor Substrate 1 Gene in One Chinese Family with Ankylosing Spondylitis

Ankylosing spondylitis (AS; MIM 106300) is a common rheumatic disease with strong genetic components affecting approximately 0.3% of the population. The exact genetic mechanism of AS remains elusive. Our previous study showed that AS could be transmitted in an autosomal dominant inheritance mode and...

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Detalles Bibliográficos
Autores principales: Rong, Ju, Li, Qiuxia, Zhang, Pingping, Wu, Xinyu, Huang, Jinxian, Li, Chao, Liao, Zetao, Xie, Yingying, Lv, Qing, Wei, Qiujing, Li, Tianwang, Huang, Jianlin, Cao, Shuangyan, Shen, Yan, Gu, Jieruo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4433214/
https://www.ncbi.nlm.nih.gov/pubmed/25978640
http://dx.doi.org/10.1371/journal.pone.0126348

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