Silencing of Receptor Tyrosine Kinase ROR1 Inhibits Tumor-Cell Proliferation via PI3K/AKT/mTOR Signaling Pathway in Lung Adenocarcinoma

Receptor tyrosine kinase ROR1, an embryonic protein involved in organogenesis, is expressed in certain hematological malignancies and solid tumors, but is generally absent in adult tissues. This makes the protein an ideal drug target for cancer therapy. In order to assess the suitability of ROR1 as...

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Detalles Bibliográficos
Autores principales: Liu, Yanchun, Yang, Hui, Chen, Tianxing, Luo, Yongbin, Xu, Zheyuan, Li, Ying, Yang, Jiahui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4433279/
https://www.ncbi.nlm.nih.gov/pubmed/25978653
http://dx.doi.org/10.1371/journal.pone.0127092

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