Validating drug repurposing signals using electronic health records: a case study of metformin associated with reduced cancer mortality

Objectives Drug repurposing, which finds new indications for existing drugs, has received great attention recently. The goal of our work is to assess the feasibility of using electronic health records (EHRs) and automated informatics methods to efficiently validate a recent drug repurposing associat...

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Detalles Bibliográficos
Autores principales: Xu, Hua, Aldrich, Melinda C, Chen, Qingxia, Liu, Hongfang, Peterson, Neeraja B, Dai, Qi, Levy, Mia, Shah, Anushi, Han, Xue, Ruan, Xiaoyang, Jiang, Min, Li, Ying, Julien, Jamii St, Warner, Jeremy, Friedman, Carol, Roden, Dan M, Denny, Joshua C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Research and Applications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4433365/
https://www.ncbi.nlm.nih.gov/pubmed/25053577
http://dx.doi.org/10.1136/amiajnl-2014-002649

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