Death Receptor 3 (TNFRSF25) Increases Mineral Apposition by Osteoblasts and Region Specific New Bone Formation in the Axial Skeleton of Male DBA/1 Mice

Objectives. Genome wide association studies identified TNFSF member TNF-like protein 1A (TL1A, TNFSF15) as a potential modulator of ankylosing spondylitis (AS). TL1A is the only confirmed TNFSF ligand of death receptor 3 (DR3, TNFRSF25); however, its role in disease pathology is not characterised. W...

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Detalles Bibliográficos
Autores principales: Collins, Fraser L., Williams, Jessica O., Bloom, Anja C., Stone, Michael D., Choy, Ernest, Wang, Eddie C. Y., Williams, Anwen S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4433704/
https://www.ncbi.nlm.nih.gov/pubmed/26065008
http://dx.doi.org/10.1155/2015/901679

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