Cargando…

Synthesis and antioxidant activity of some 1-aryl/aralkyl piperazine derivatives with xanthine moiety at N4

Piperazine nucleus is one of the most important heterocyclic systems exhibiting remarkable pharmacological activities. Thus, in the current study six new aryl/aralkyl substituted piperazine derivatives, containing methylxanthine moiety were synthesized and their structures were confirmed by IR and (...

Descripción completa

Detalles Bibliográficos
Autores principales:	Andonova, Lily, Zheleva-Dimitrova, Dimitrina, Georgieva, Maya, Zlatkov, Alexander
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2014
Materias:	Article; Pharmaceutical Biotechnology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4433850/ https://www.ncbi.nlm.nih.gov/pubmed/26019603 http://dx.doi.org/10.1080/13102818.2014.979978

Ejemplares similares

Low cytotoxicity and clastogenicity of some polymeric aminophosphonate derivatives
por: Kril, Anton, et al.
Publicado: (2014)

Synthesis, characterization and antibacterial assessment of SiO(2)-hydroxypropylmethyl cellulose hybrid materials with embedded silver nanoparticles
por: Angelova, Tsvetelina, et al.
Publicado: (2014)

Biological evaluation of new potential anticancer agent for tumour imaging and radiotherapy by two methods: (99m)Tc-radiolabelling and EPR spectroscopy
por: Karamalakova, Yanka, et al.
Publicado: (2014)

Antioxidant and acetylcholinesterase inhibition properties of Amorpha fruticosa L. and Phytolacca americana L.
por: Zheleva-Dimitrova, Dimitrina Zh.
Publicado: (2013)

N-alkyl/aralkyl-4-(3-substituted-3-phenylpropyl)piperazine-1-carbodithioate derivatives to tackle resistant trichomoniasis
por: Bala, V, et al.
Publicado: (2015)

Design, Synthesis, and Biological Evaluation of Novel Benzofuran Derivatives Bearing N-Aryl Piperazine Moiety
por: Ma, Yulu, et al.
Publicado: (2016)

Antibacterial and antitumour activities of some plants grown in Turkey
por: Usta, Canan, et al.
Publicado: (2014)

Quantitative Structure–Neurotoxicity Assessment and In Vitro Evaluation of Neuroprotective and MAO-B Inhibitory Activities of Series N′-substituted 3-(1,3,7-trimethyl-xanthin-8-ylthio)propanehydrazides
por: Kondeva-Burdina, Magdalena, et al.
Publicado: (2022)

Benzophenones from Hypericum elegans with antioxidant and acetylcholinesterase inhibitory potential
por: Zheleva-Dimitrova, Dimitrina, et al.
Publicado: (2013)

Effect of Silicone on the Collagen Fibrillogenesis and Stability
por: Kadziński, Leszek, et al.
Publicado: (2015)

Understanding the Relationship Between Biotherapeutic Protein Stability and Solid–Liquid Interfacial Shear in Constant Region Mutants of IgG1 and IgG4
por: Tavakoli-Keshe, Roumteen, et al.
Publicado: (2014)

Control of Protein Particle Formation During Ultrafiltration/Diafiltration Through Interfacial Protection
por: Callahan, Daniel J, et al.
Publicado: (2014)

Quantitative Laser Diffraction Method for the Assessment of Protein Subvisible Particles
por: Totoki, Shinichiro, et al.
Publicado: (2015)

Effects of Syringe Material and Silicone Oil Lubrication on the Stability of Pharmaceutical Proteins
por: Krayukhina, Elena, et al.
Publicado: (2015)

Characterizing and Minimizing Aggregation and Particle Formation of Three Recombinant Fusion-Protein Bulk Antigens for Use in a Candidate Trivalent Rotavirus Vaccine
por: Agarwal, Sanjeev, et al.
Publicado: (2020)

Recombinant Subunit Rotavirus Trivalent Vaccine Candidate: Physicochemical Comparisons and Stability Evaluations of Three Protein Antigens
por: Agarwal, Sanjeev, et al.
Publicado: (2019)

Changes in Expression Pattern of SEMA3F Depending on Endometrial Cancer Grade - Pilot Study
por: Dziobek, Konrad, et al.
Publicado: (2019)

Measurement of Adenovirus-Based Vector Heterogeneity
por: Hickey, John M., et al.
Publicado: (2023)

Characterization of BNT162b2 mRNA to Evaluate Risk of Off-Target Antigen Translation
por: Patel, Himakshi K., et al.
Publicado: (2023)

Radical scavenging and antioxidant activities of methanolic extracts from Hypericum species growing in Bulgaria
por: Zheleva-Dimitrova, Dimitrina, et al.
Publicado: (2010)

Changes in the functional characteristics of tumor and normal cells after treatment with extracts of white dead-nettle
por: Veleva, Ralitsa, et al.
Publicado: (2015)

Biological evaluation of synthesized allicin and its transformation products obtained by microwaves in methanol: antioxidant activity and effect on cell growth
por: Ilić, Dušica P., et al.
Publicado: (2015)

Synthesis of N-Mannich bases of berberine linking piperazine moieties revealing anticancer and antioxidant effects
por: Mistry, Bhupendra, et al.
Publicado: (2017)

Synthesis and Antimicrobial Activity of New Mannich Bases with Piperazine Moiety
por: Janowska, Sara, et al.
Publicado: (2023)

Cytoprotective and antioxidant effects of phenolic compounds from Haberlea rhodopensis Friv. (Gesneriaceae)
por: Kondeva-Burdina, Magdalena, et al.
Publicado: (2013)

Synthesis of Some New Isoxazoline Derivatives of Chalconised Indoline 2-one as a Potential Analgesic, Antibacterial and Anthelmimtic Agents
por: Mondal, P, et al.
Publicado: (2012)

Synthesis and in vitro activity of platinum(II) complexes of two fluorenylspirohydantoins against a human tumour cell line
por: Marinova, Petja, et al.
Publicado: (2014)

Synthesis and Antifungal Activity of Novel Triazole Compounds Containing Piperazine Moiety
por: Wang, Yanwei, et al.
Publicado: (2014)

Encapsulation of Naproxen in Lipid-Based Matrix Microspheres: Characterization and Release Kinetics
por: Bhoyar, PK, et al.
Publicado: (2011)

Taste Masking and Molecular Properties of Metformin Hydrochloride-Indion 234 Complexes
por: Bhoyar, PK, et al.
Publicado: (2011)

Formulation, In Vitro and In Vivo Pharmacokinetics of Anti-HIV Vaginal Bioadhesive Gel
por: Chatterjee, A, et al.
Publicado: (2011)

Multiple Unit Particles System of Ramipril: An Approach to Enhance Stability
por: Patel, HP, et al.
Publicado: (2011)

Preparation and in vitro Characterization of Porous Carrier–Based Glipizide Floating Microspheres for Gastric Delivery
por: Pandya, N, et al.
Publicado: (2011)

Design of vitamin E d-α-Tocopheryl Polyethylene Glycol 1000 Succinate-Emulsified Poly (D,L–Lactide–co-Glycolide) Nanoparticles: Influence of Duration of Ultrasonication Energy
por: Şengel, CT, et al.
Publicado: (2011)

Design of Controlled Release Non-erodible Polymeric Matrix Tablet Using Microwave Oven-assisted Sintering Technique
por: Patel, DM, et al.
Publicado: (2011)

Dissofilm: A Novel Approach for Delivery of Phenobarbital; Design and Characterization
por: Yellanki, SK, et al.
Publicado: (2011)

Preparation and Evaluation of Mixture of Eudragit and Ethylcellulose Microparticles Loaded with Ranolazine for Controlled Release
por: Gowda, DV, et al.
Publicado: (2011)

Preparation and Characterization of Metformin Hydrochloride — Compritol 888 ATO Solid Dispersion
por: Jagdale, SC, et al.
Publicado: (2011)

Preparation and Evaluation of Silymarin β-cyclodextrin Molecular Inclusion Complexes
por: Ghosh, A, et al.
Publicado: (2011)

Hordeum Vulgare Hull in the Design of Fast Disintegrating Tablets
por: Rajpurohit, H, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_sa9oeunkob4kkf4qnj7jo396fs