A spot-matching method using cumulative frequency matrix in 2D gel images

A new method for spot matching in two-dimensional gel electrophoresis images using a cumulative frequency matrix is proposed. The method improves on the weak points of the previous method called ‘spot matching by topological patterns of neighbour spots’. It accumulates the frequencies of neighbour s...

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Detalles Bibliográficos
Autores principales: Han, Chan-Myeong, Park, Joon-Ho, Chang, Chu-Seok, Ryoo, Myung-Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2014
Materias:
Article; Bioinformatics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4434135/
https://www.ncbi.nlm.nih.gov/pubmed/26019609
http://dx.doi.org/10.1080/13102818.2014.949036
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author Han, Chan-Myeong
Park, Joon-Ho
Chang, Chu-Seok
Ryoo, Myung-Chun
author_facet Han, Chan-Myeong
Park, Joon-Ho
Chang, Chu-Seok
Ryoo, Myung-Chun
author_sort Han, Chan-Myeong
collection PubMed
description A new method for spot matching in two-dimensional gel electrophoresis images using a cumulative frequency matrix is proposed. The method improves on the weak points of the previous method called ‘spot matching by topological patterns of neighbour spots’. It accumulates the frequencies of neighbour spot pairs produced through the entire matching process and determines spot pairs one by one in order of higher frequency. Spot matching by frequencies of neighbour spot pairs shows a fairly better performance. However, it can give researchers a hint for whether the matching results can be trustworthy or not, which can save researchers a lot of effort for verification of the results.
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spelling pubmed-44341352015-05-25 A spot-matching method using cumulative frequency matrix in 2D gel images Han, Chan-Myeong Park, Joon-Ho Chang, Chu-Seok Ryoo, Myung-Chun Biotechnol Biotechnol Equip Article; Bioinformatics A new method for spot matching in two-dimensional gel electrophoresis images using a cumulative frequency matrix is proposed. The method improves on the weak points of the previous method called ‘spot matching by topological patterns of neighbour spots’. It accumulates the frequencies of neighbour spot pairs produced through the entire matching process and determines spot pairs one by one in order of higher frequency. Spot matching by frequencies of neighbour spot pairs shows a fairly better performance. However, it can give researchers a hint for whether the matching results can be trustworthy or not, which can save researchers a lot of effort for verification of the results. Taylor & Francis 2014-11-14 2014-11-28 /pmc/articles/PMC4434135/ /pubmed/26019609 http://dx.doi.org/10.1080/13102818.2014.949036 Text en © 2014 The Author(s). Published by Taylor & Francis. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The moral rights of the named author(s) have been asserted.
spellingShingle Article; Bioinformatics
Han, Chan-Myeong
Park, Joon-Ho
Chang, Chu-Seok
Ryoo, Myung-Chun
A spot-matching method using cumulative frequency matrix in 2D gel images
title A spot-matching method using cumulative frequency matrix in 2D gel images
title_full A spot-matching method using cumulative frequency matrix in 2D gel images
title_fullStr A spot-matching method using cumulative frequency matrix in 2D gel images
title_full_unstemmed A spot-matching method using cumulative frequency matrix in 2D gel images
title_short A spot-matching method using cumulative frequency matrix in 2D gel images
title_sort spot-matching method using cumulative frequency matrix in 2d gel images
topic Article; Bioinformatics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4434135/
https://www.ncbi.nlm.nih.gov/pubmed/26019609
http://dx.doi.org/10.1080/13102818.2014.949036
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