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A Rare Cutaneous Adnexal Tumor: Malignant Proliferating Trichilemmal Tumor
Proliferating trichilemmal tumors (PTTs) are neoplasms derived from the outer root sheath of the hair follicle. These tumors, which commonly affect the scalp of elderly women, rarely demonstrate malignant transformation. Although invasion of the tumors into neighboring tissues and being accompanied...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4434212/ https://www.ncbi.nlm.nih.gov/pubmed/26064131 http://dx.doi.org/10.1155/2015/742920 |
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author | Alici, Omer Keles, Musa Kemal Kurt, Alper |
author_facet | Alici, Omer Keles, Musa Kemal Kurt, Alper |
author_sort | Alici, Omer |
collection | PubMed |
description | Proliferating trichilemmal tumors (PTTs) are neoplasms derived from the outer root sheath of the hair follicle. These tumors, which commonly affect the scalp of elderly women, rarely demonstrate malignant transformation. Although invasion of the tumors into neighboring tissues and being accompanied with anaplasia and necrosis are accepted as findings of malignancy, histological features may not always be sufficient to identify these tumors. The clinical behavior of the tumor may be incompatible with its histological characteristics. Squamous-cell carcinoma should certainly be considered in differential diagnosis because of its similarity in morphological appearance with PTT. Immunostaining for CD34, P53, and Ki-67 is a useful adjuvant diagnostic method that can be used in differential diagnosis aside from morphological findings. In this study, we aimed to present the case of a 52-year-old female patient with clinicopathological features. We reported a low-grade malignant proliferating trichilemmal tumor in this patient and detected no relapse or metastasis in a 24-month period of follow-up. |
format | Online Article Text |
id | pubmed-4434212 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-44342122015-06-10 A Rare Cutaneous Adnexal Tumor: Malignant Proliferating Trichilemmal Tumor Alici, Omer Keles, Musa Kemal Kurt, Alper Case Rep Med Case Report Proliferating trichilemmal tumors (PTTs) are neoplasms derived from the outer root sheath of the hair follicle. These tumors, which commonly affect the scalp of elderly women, rarely demonstrate malignant transformation. Although invasion of the tumors into neighboring tissues and being accompanied with anaplasia and necrosis are accepted as findings of malignancy, histological features may not always be sufficient to identify these tumors. The clinical behavior of the tumor may be incompatible with its histological characteristics. Squamous-cell carcinoma should certainly be considered in differential diagnosis because of its similarity in morphological appearance with PTT. Immunostaining for CD34, P53, and Ki-67 is a useful adjuvant diagnostic method that can be used in differential diagnosis aside from morphological findings. In this study, we aimed to present the case of a 52-year-old female patient with clinicopathological features. We reported a low-grade malignant proliferating trichilemmal tumor in this patient and detected no relapse or metastasis in a 24-month period of follow-up. Hindawi Publishing Corporation 2015 2015-05-04 /pmc/articles/PMC4434212/ /pubmed/26064131 http://dx.doi.org/10.1155/2015/742920 Text en Copyright © 2015 Omer Alici et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Alici, Omer Keles, Musa Kemal Kurt, Alper A Rare Cutaneous Adnexal Tumor: Malignant Proliferating Trichilemmal Tumor |
title | A Rare Cutaneous Adnexal Tumor: Malignant Proliferating Trichilemmal Tumor |
title_full | A Rare Cutaneous Adnexal Tumor: Malignant Proliferating Trichilemmal Tumor |
title_fullStr | A Rare Cutaneous Adnexal Tumor: Malignant Proliferating Trichilemmal Tumor |
title_full_unstemmed | A Rare Cutaneous Adnexal Tumor: Malignant Proliferating Trichilemmal Tumor |
title_short | A Rare Cutaneous Adnexal Tumor: Malignant Proliferating Trichilemmal Tumor |
title_sort | rare cutaneous adnexal tumor: malignant proliferating trichilemmal tumor |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4434212/ https://www.ncbi.nlm.nih.gov/pubmed/26064131 http://dx.doi.org/10.1155/2015/742920 |
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