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Cochlear progenitor number is controlled through mesenchymal FGF receptor signaling

The sensory and supporting cells (SCs) of the organ of Corti are derived from a limited number of progenitors. The mechanisms that regulate the number of sensory progenitors are not known. Here, we show that Fibroblast Growth Factors (FGF) 9 and 20, which are expressed in the non-sensory (Fgf9) and...

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Detalles Bibliográficos
Autores principales: Huh, Sung-Ho, Warchol, Mark E, Ornitz, David M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4434254/
https://www.ncbi.nlm.nih.gov/pubmed/25915623
http://dx.doi.org/10.7554/eLife.05921