Leptin and its cardiovascular effects: Focus on angiogenesis

Leptin is an endocrine hormone synthesized by adipocytes. It plays a key role in the energy homeostasis in central and peripheral tissues and has additional roles are attributed to it, such as the regulation of reproduction, immune function, bone homeostasis, and angiogenesis. The plasma concentrati...

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Detalles Bibliográficos
Autores principales: Tahergorabi, Zoya, Khazaei, Majid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4434486/
https://www.ncbi.nlm.nih.gov/pubmed/26015905
http://dx.doi.org/10.4103/2277-9175.156526
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author Tahergorabi, Zoya
Khazaei, Majid
author_facet Tahergorabi, Zoya
Khazaei, Majid
author_sort Tahergorabi, Zoya
collection PubMed
description Leptin is an endocrine hormone synthesized by adipocytes. It plays a key role in the energy homeostasis in central and peripheral tissues and has additional roles are attributed to it, such as the regulation of reproduction, immune function, bone homeostasis, and angiogenesis. The plasma concentration of leptin significantly increases in obese individuals. In the present review, we give an introduction concerning leptin, its receptors, signaling pathways, and its effect on cardiovascular system, especially on angiogenesis.
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spelling pubmed-44344862015-05-26 Leptin and its cardiovascular effects: Focus on angiogenesis Tahergorabi, Zoya Khazaei, Majid Adv Biomed Res Review Article Leptin is an endocrine hormone synthesized by adipocytes. It plays a key role in the energy homeostasis in central and peripheral tissues and has additional roles are attributed to it, such as the regulation of reproduction, immune function, bone homeostasis, and angiogenesis. The plasma concentration of leptin significantly increases in obese individuals. In the present review, we give an introduction concerning leptin, its receptors, signaling pathways, and its effect on cardiovascular system, especially on angiogenesis. Medknow Publications & Media Pvt Ltd 2015-05-06 /pmc/articles/PMC4434486/ /pubmed/26015905 http://dx.doi.org/10.4103/2277-9175.156526 Text en Copyright: © 2015 Tahergorabi http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Review Article
Tahergorabi, Zoya
Khazaei, Majid
Leptin and its cardiovascular effects: Focus on angiogenesis
title Leptin and its cardiovascular effects: Focus on angiogenesis
title_full Leptin and its cardiovascular effects: Focus on angiogenesis
title_fullStr Leptin and its cardiovascular effects: Focus on angiogenesis
title_full_unstemmed Leptin and its cardiovascular effects: Focus on angiogenesis
title_short Leptin and its cardiovascular effects: Focus on angiogenesis
title_sort leptin and its cardiovascular effects: focus on angiogenesis
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4434486/
https://www.ncbi.nlm.nih.gov/pubmed/26015905
http://dx.doi.org/10.4103/2277-9175.156526
work_keys_str_mv AT tahergorabizoya leptinanditscardiovasculareffectsfocusonangiogenesis
AT khazaeimajid leptinanditscardiovasculareffectsfocusonangiogenesis

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