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Licochalcone A-induced human gastric cancer BGC-823 cells apoptosis by regulating ROS-mediated MAPKs and PI3K/AKT signaling pathways
Both phosphatidylinositol 3-kinase (PI3K)/AKT and mitogen activated protein kinase (MAPK) signaling cascades play an important role in cell proliferation, survival, angiogenesis, and metastasis of tumor cells. In the present report, we investigated the effects of licochalcone A (LA), a flavonoid ext...
Autores principales: | Hao, Wenjin, Yuan, Xuan, Yu, Lina, Gao, Caixia, Sun, Xiling, Wang, Dong, Zheng, Qiusheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4434846/ https://www.ncbi.nlm.nih.gov/pubmed/25981581 http://dx.doi.org/10.1038/srep10336 |
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