Cargando…

The Smc5-Smc6 heterodimer associates with DNA through several independent binding domains

The Smc5-6 complex is required for the maintenance of genome integrity through its functions in DNA repair and chromosome biogenesis. However, the specific mode of action of Smc5 and Smc6 in these processes remains largely unknown. We previously showed that individual components of the Smc5-Smc6 com...

Descripción completa

Detalles Bibliográficos
Autores principales: Roy, Marc-André, Dhanaraman, Thillaivillalan, D’Amours, Damien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4434891/
https://www.ncbi.nlm.nih.gov/pubmed/25984708
http://dx.doi.org/10.1038/srep09797