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The Smc5-Smc6 heterodimer associates with DNA through several independent binding domains
The Smc5-6 complex is required for the maintenance of genome integrity through its functions in DNA repair and chromosome biogenesis. However, the specific mode of action of Smc5 and Smc6 in these processes remains largely unknown. We previously showed that individual components of the Smc5-Smc6 com...
Autores principales: | Roy, Marc-André, Dhanaraman, Thillaivillalan, D’Amours, Damien |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4434891/ https://www.ncbi.nlm.nih.gov/pubmed/25984708 http://dx.doi.org/10.1038/srep09797 |
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