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In vitro properties of designed antimicrobial peptides that exhibit potent antipneumococcal activity and produces synergism in combination with penicillin
Antimicrobial peptides (AMPs) represent a promising class of novel antimicrobial agents owing to their potent antimicrobial activity. In this study, two lead peptides from unrelated classes of AMPs were systematically hybridized into a series of five hybrid peptides (DM1- DM5) with conserved N- and...
Autores principales: | Le, Cheng-Foh, Yusof, Mohd Yasim Mohd, Hassan, Hamimah, Sekaran, Shamala Devi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4434909/ https://www.ncbi.nlm.nih.gov/pubmed/25985150 http://dx.doi.org/10.1038/srep09761 |
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