Basal protein phosphatase 2A activity restrains cytokine expression: role for MAPKs and tristetraprolin

PP2A is a master controller of multiple inflammatory signaling pathways. It is a target in asthma; however the molecular mechanisms by which PP2A controls inflammation warrant further investigation. In A549 lung epithelial cells in vitro we show that inhibition of basal PP2A activity by okadaic acid...

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Detalles Bibliográficos
Autores principales: Rahman, Md. Mostafizur, Rumzhum, Nowshin N., Morris, Jonathan C., Clark, Andrew R., Verrills, Nicole M., Ammit, Alaina J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4434956/
https://www.ncbi.nlm.nih.gov/pubmed/25985190
http://dx.doi.org/10.1038/srep10063

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