Cargando…
ANTIFUNGAL ACTIVITY OF SILVER NANOPARTICLES OBTAINED BY GREEN SYNTHESIS
Silver nanoparticles (AgNPs) are metal structures at the nanoscale. AgNPs have exhibited antimicrobial activities against fungi and bacteria; however synthesis of AgNPs can generate toxic waste during the reaction process. Accordingly, new routes using non-toxic compounds have been researched. The p...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Instituto de Medicina Tropical
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4435016/ https://www.ncbi.nlm.nih.gov/pubmed/25923897 http://dx.doi.org/10.1590/S0036-46652015000200011 |
_version_ | 1782371836305080320 |
---|---|
author | MALLMANN, Eduardo José J. CUNHA, Francisco Afrânio CASTRO, Bruno N.M.F. MACIEL, Auberson Martins MENEZES, Everardo Albuquerque FECHINE, Pierre Basílio Almeida |
author_facet | MALLMANN, Eduardo José J. CUNHA, Francisco Afrânio CASTRO, Bruno N.M.F. MACIEL, Auberson Martins MENEZES, Everardo Albuquerque FECHINE, Pierre Basílio Almeida |
author_sort | MALLMANN, Eduardo José J. |
collection | PubMed |
description | Silver nanoparticles (AgNPs) are metal structures at the nanoscale. AgNPs have exhibited antimicrobial activities against fungi and bacteria; however synthesis of AgNPs can generate toxic waste during the reaction process. Accordingly, new routes using non-toxic compounds have been researched. The proposal of the present study was to synthesize AgNPs using ribose as a reducing agent and sodium dodecyl sulfate (SDS) as a stabilizer. The antifungal activity of these particles against C. albicans and C. tropicalis was also evaluated. Stable nanoparticles 12.5 ± 4.9 nm (mean ± SD) in size were obtained, which showed high activity against Candida spp. and could represent an alternative for fungal infection treatment. |
format | Online Article Text |
id | pubmed-4435016 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Instituto de Medicina Tropical |
record_format | MEDLINE/PubMed |
spelling | pubmed-44350162015-05-18 ANTIFUNGAL ACTIVITY OF SILVER NANOPARTICLES OBTAINED BY GREEN SYNTHESIS MALLMANN, Eduardo José J. CUNHA, Francisco Afrânio CASTRO, Bruno N.M.F. MACIEL, Auberson Martins MENEZES, Everardo Albuquerque FECHINE, Pierre Basílio Almeida Rev Inst Med Trop Sao Paulo Brief Communications Silver nanoparticles (AgNPs) are metal structures at the nanoscale. AgNPs have exhibited antimicrobial activities against fungi and bacteria; however synthesis of AgNPs can generate toxic waste during the reaction process. Accordingly, new routes using non-toxic compounds have been researched. The proposal of the present study was to synthesize AgNPs using ribose as a reducing agent and sodium dodecyl sulfate (SDS) as a stabilizer. The antifungal activity of these particles against C. albicans and C. tropicalis was also evaluated. Stable nanoparticles 12.5 ± 4.9 nm (mean ± SD) in size were obtained, which showed high activity against Candida spp. and could represent an alternative for fungal infection treatment. Instituto de Medicina Tropical 2015 /pmc/articles/PMC4435016/ /pubmed/25923897 http://dx.doi.org/10.1590/S0036-46652015000200011 Text en http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Brief Communications MALLMANN, Eduardo José J. CUNHA, Francisco Afrânio CASTRO, Bruno N.M.F. MACIEL, Auberson Martins MENEZES, Everardo Albuquerque FECHINE, Pierre Basílio Almeida ANTIFUNGAL ACTIVITY OF SILVER NANOPARTICLES OBTAINED BY GREEN SYNTHESIS |
title | ANTIFUNGAL ACTIVITY OF SILVER NANOPARTICLES OBTAINED BY GREEN
SYNTHESIS |
title_full | ANTIFUNGAL ACTIVITY OF SILVER NANOPARTICLES OBTAINED BY GREEN
SYNTHESIS |
title_fullStr | ANTIFUNGAL ACTIVITY OF SILVER NANOPARTICLES OBTAINED BY GREEN
SYNTHESIS |
title_full_unstemmed | ANTIFUNGAL ACTIVITY OF SILVER NANOPARTICLES OBTAINED BY GREEN
SYNTHESIS |
title_short | ANTIFUNGAL ACTIVITY OF SILVER NANOPARTICLES OBTAINED BY GREEN
SYNTHESIS |
title_sort | antifungal activity of silver nanoparticles obtained by green
synthesis |
topic | Brief Communications |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4435016/ https://www.ncbi.nlm.nih.gov/pubmed/25923897 http://dx.doi.org/10.1590/S0036-46652015000200011 |
work_keys_str_mv | AT mallmanneduardojosej antifungalactivityofsilvernanoparticlesobtainedbygreensynthesis AT cunhafranciscoafranio antifungalactivityofsilvernanoparticlesobtainedbygreensynthesis AT castrobrunonmf antifungalactivityofsilvernanoparticlesobtainedbygreensynthesis AT macielaubersonmartins antifungalactivityofsilvernanoparticlesobtainedbygreensynthesis AT menezeseverardoalbuquerque antifungalactivityofsilvernanoparticlesobtainedbygreensynthesis AT fechinepierrebasilioalmeida antifungalactivityofsilvernanoparticlesobtainedbygreensynthesis |