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ANTIFUNGAL ACTIVITY OF SILVER NANOPARTICLES OBTAINED BY GREEN SYNTHESIS

Silver nanoparticles (AgNPs) are metal structures at the nanoscale. AgNPs have exhibited antimicrobial activities against fungi and bacteria; however synthesis of AgNPs can generate toxic waste during the reaction process. Accordingly, new routes using non-toxic compounds have been researched. The p...

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Autores principales: MALLMANN, Eduardo José J., CUNHA, Francisco Afrânio, CASTRO, Bruno N.M.F., MACIEL, Auberson Martins, MENEZES, Everardo Albuquerque, FECHINE, Pierre Basílio Almeida
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Instituto de Medicina Tropical 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4435016/
https://www.ncbi.nlm.nih.gov/pubmed/25923897
http://dx.doi.org/10.1590/S0036-46652015000200011
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author MALLMANN, Eduardo José J.
CUNHA, Francisco Afrânio
CASTRO, Bruno N.M.F.
MACIEL, Auberson Martins
MENEZES, Everardo Albuquerque
FECHINE, Pierre Basílio Almeida
author_facet MALLMANN, Eduardo José J.
CUNHA, Francisco Afrânio
CASTRO, Bruno N.M.F.
MACIEL, Auberson Martins
MENEZES, Everardo Albuquerque
FECHINE, Pierre Basílio Almeida
author_sort MALLMANN, Eduardo José J.
collection PubMed
description Silver nanoparticles (AgNPs) are metal structures at the nanoscale. AgNPs have exhibited antimicrobial activities against fungi and bacteria; however synthesis of AgNPs can generate toxic waste during the reaction process. Accordingly, new routes using non-toxic compounds have been researched. The proposal of the present study was to synthesize AgNPs using ribose as a reducing agent and sodium dodecyl sulfate (SDS) as a stabilizer. The antifungal activity of these particles against C. albicans and C. tropicalis was also evaluated. Stable nanoparticles 12.5 ± 4.9 nm (mean ± SD) in size were obtained, which showed high activity against Candida spp. and could represent an alternative for fungal infection treatment.
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spelling pubmed-44350162015-05-18 ANTIFUNGAL ACTIVITY OF SILVER NANOPARTICLES OBTAINED BY GREEN SYNTHESIS MALLMANN, Eduardo José J. CUNHA, Francisco Afrânio CASTRO, Bruno N.M.F. MACIEL, Auberson Martins MENEZES, Everardo Albuquerque FECHINE, Pierre Basílio Almeida Rev Inst Med Trop Sao Paulo Brief Communications Silver nanoparticles (AgNPs) are metal structures at the nanoscale. AgNPs have exhibited antimicrobial activities against fungi and bacteria; however synthesis of AgNPs can generate toxic waste during the reaction process. Accordingly, new routes using non-toxic compounds have been researched. The proposal of the present study was to synthesize AgNPs using ribose as a reducing agent and sodium dodecyl sulfate (SDS) as a stabilizer. The antifungal activity of these particles against C. albicans and C. tropicalis was also evaluated. Stable nanoparticles 12.5 ± 4.9 nm (mean ± SD) in size were obtained, which showed high activity against Candida spp. and could represent an alternative for fungal infection treatment. Instituto de Medicina Tropical 2015 /pmc/articles/PMC4435016/ /pubmed/25923897 http://dx.doi.org/10.1590/S0036-46652015000200011 Text en http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Brief Communications
MALLMANN, Eduardo José J.
CUNHA, Francisco Afrânio
CASTRO, Bruno N.M.F.
MACIEL, Auberson Martins
MENEZES, Everardo Albuquerque
FECHINE, Pierre Basílio Almeida
ANTIFUNGAL ACTIVITY OF SILVER NANOPARTICLES OBTAINED BY GREEN SYNTHESIS
title ANTIFUNGAL ACTIVITY OF SILVER NANOPARTICLES OBTAINED BY GREEN SYNTHESIS
title_full ANTIFUNGAL ACTIVITY OF SILVER NANOPARTICLES OBTAINED BY GREEN SYNTHESIS
title_fullStr ANTIFUNGAL ACTIVITY OF SILVER NANOPARTICLES OBTAINED BY GREEN SYNTHESIS
title_full_unstemmed ANTIFUNGAL ACTIVITY OF SILVER NANOPARTICLES OBTAINED BY GREEN SYNTHESIS
title_short ANTIFUNGAL ACTIVITY OF SILVER NANOPARTICLES OBTAINED BY GREEN SYNTHESIS
title_sort antifungal activity of silver nanoparticles obtained by green synthesis
topic Brief Communications
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4435016/
https://www.ncbi.nlm.nih.gov/pubmed/25923897
http://dx.doi.org/10.1590/S0036-46652015000200011
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