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Accelerated Apoptosis of Neutrophils in Familial Mediterranean Fever

The causative mutations for familial Mediterranean fever (FMF) are located in the MEFV gene, which encodes pyrin. Pyrin modulates the susceptibility to apoptosis via its PYD domain, but how the mutated versions of pyrin affect apoptotic processes are poorly understood. Spontaneous and induced rates...

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Detalles Bibliográficos
Autores principales:	Manukyan, Gayane, Aminov, Rustam, Hakobyan, Gagik, Davtyan, Tigran
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2015
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4435041/ https://www.ncbi.nlm.nih.gov/pubmed/26042122 http://dx.doi.org/10.3389/fimmu.2015.00239

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