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Discovery of MINC1, a GTPase-Activating Protein Small Molecule Inhibitor, Targeting MgcRacGAP

The Rho family of Ras superfamily small GTPases regulates a broad range of biological processes such as migration, differentiation, cell growth and cell survival. Therefore, the availability of small molecule modulators as tool compounds could greatly enhance research on these proteins and their bio...

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Detalles Bibliográficos
Autores principales: van Adrichem, Arjan J., Fagerholm, Annika, Turunen, Laura, Lehto, Anna, Saarela, Jani, Koskinen, Ari, Repasky, Gretchen A., Wennerberg, Krister
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4435052/
https://www.ncbi.nlm.nih.gov/pubmed/25479424
http://dx.doi.org/10.2174/1386207318666141205112730