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Discovery of MINC1, a GTPase-Activating Protein Small Molecule Inhibitor, Targeting MgcRacGAP
The Rho family of Ras superfamily small GTPases regulates a broad range of biological processes such as migration, differentiation, cell growth and cell survival. Therefore, the availability of small molecule modulators as tool compounds could greatly enhance research on these proteins and their bio...
Autores principales: | van Adrichem, Arjan J., Fagerholm, Annika, Turunen, Laura, Lehto, Anna, Saarela, Jani, Koskinen, Ari, Repasky, Gretchen A., Wennerberg, Krister |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Bentham Science Publishers
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4435052/ https://www.ncbi.nlm.nih.gov/pubmed/25479424 http://dx.doi.org/10.2174/1386207318666141205112730 |
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