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Pleiotropic Role of HSF1 in Neoplastic Transformation

HSF1 (Heat Shock transcription Factor 1) is the main transcription factor activated in response to proteotoxic stress. Once activated, it induces an expression of heat shock proteins (HSPs) which enables cells to survive in suboptimal conditions. HSF1 could be also activated by altered kinase signal...

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Detalles Bibliográficos
Autores principales: Vydra, Natalia, Toma, Agnieszka, Widlak, Wieslawa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4435066/
https://www.ncbi.nlm.nih.gov/pubmed/24467529
http://dx.doi.org/10.2174/1568009614666140122155942