Cargando…

Development of a Microfluidic-Based Optical Sensing Device for Label-Free Detection of Circulating Tumor Cells (CTCs) Through Their Lactic Acid Metabolism

This study reports a microfluidic-based optical sensing device for label-free detection of circulating tumor cells (CTCs), a rare cell species in blood circulation. Based on the metabolic features of cancer cells, live CTCs can be quantified indirectly through their lactic acid production. Compared...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chiu, Tzu-Keng, Lei, Kin-Fong, Hsieh, Chia-Hsun, Hsiao, Hung-Bo, Wang, Hung-Ming, Wu, Min-Hsien
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4435186/ https://www.ncbi.nlm.nih.gov/pubmed/25808775 http://dx.doi.org/10.3390/s150306789

Ejemplares similares

The Combination of Immunomagnetic Bead-Based Cell Isolation and Optically Induced Dielectrophoresis (ODEP)-Based Microfluidic Device for the Negative Selection-Based Isolation of Circulating Tumor Cells (CTCs)
por: Chu, Po-Yu, et al.
Publicado: (2020)

Application of optically-induced-dielectrophoresis in microfluidic system for purification of circulating tumour cells for gene expression analysis- Cancer cell line model
por: Chiu, Tzu-Keng, et al.
Publicado: (2016)

Design and Simulation of an Integrated Centrifugal Microfluidic Device for CTCs Separation and Cell Lysis
por: Nasiri, Rohollah, et al.
Publicado: (2020)

The Integration of a Three-Dimensional Spheroid Cell Culture Operation in a Circulating Tumor Cell (CTC) Isolation and Purification Process: A Preliminary Study of the Clinical Significance and Prognostic Role of the CTCs Isolated from the Blood Samples of Head and Neck Cancer Patients
por: Liao, Chia-Jung, et al.
Publicado: (2019)

Development of an Automated and Sensitive Microfluidic Device for Capturing and Characterizing Circulating Tumor Cells (CTCs) from Clinical Blood Samples
por: Gogoi, Priya, et al.
Publicado: (2016)

Detection and prognostic relevance of circulating tumour cells (CTCs) in Asian breast cancers using a label-free microfluidic platform
por: Yap, Yoon-Sim, et al.
Publicado: (2019)

An Optically Induced Dielectrophoresis (ODEP)-Based Microfluidic System for the Isolation of High-Purity CD45(neg)/EpCAM(neg) Cells from the Blood Samples of Cancer Patients—Demonstration and Initial Exploration of the Clinical Significance of These Cells
por: Liao, Chia-Jung, et al.
Publicado: (2018)

Design of a Hybrid Inertial and Magnetophoretic Microfluidic Device for CTCs Separation from Blood
por: Nasiri, Rohollah, et al.
Publicado: (2021)

Recent Progress in Enhanced Cancer Diagnosis, Prognosis, and Monitoring Using a Combined Analysis of the Number of Circulating Tumor Cells (CTCs) and Other Clinical Parameters
por: Nguyen, Thi Ngoc Anh, et al.
Publicado: (2023)

Circulating tumor cells (CTCs) and hTERT gene expression in CTCs for radiotherapy effect with lung cancer
por: Xu, Ying, et al.
Publicado: (2023)

A label-free microfluidic chip for the highly selective isolation of single and cluster CTCs from breast cancer patients
por: Zhang, Xiaofen, et al.
Publicado: (2020)

Microfluidics and Nanomaterial-based Technologies for Circulating Tumor Cell Isolation and Detection
por: Cheng, Sheng-Jen, et al.
Publicado: (2020)

Ex vivo expansion of circulating tumour cells (CTCs)
por: Mohamed, Bashir M., et al.
Publicado: (2023)

The Characteristics Analysis of a Microfluid-Based EGFET Biosensor with On-Chip Sensing Film for Lactic Acid Detection
por: Kuo, Po-Yu, et al.
Publicado: (2022)

Apoptotic circulating tumor cells (CTCs) in the peripheral blood of metastatic colorectal cancer patients are associated with liver metastasis but not CTCs
por: Allen, Joshua E., et al.
Publicado: (2013)

A novel microchannel-based device to capture and analyze circulating tumor cells (CTCs) of breast cancer
por: RIAHI, REZA, et al.
Publicado: (2014)

The Prognostic Role of Circulating Tumor Cells (CTCs) in Lung Cancer
por: Kapeleris, Joanna, et al.
Publicado: (2018)

Fugitives on the run: circulating tumor cells (CTCs) in metastatic diseases
por: Mamdouhi, Tania, et al.
Publicado: (2019)

A High-Throughput Automated Microfluidic Platform for Calcium Imaging of Taste Sensing
por: Hsiao, Yi-Hsing, et al.
Publicado: (2016)

A microfluidic device for label-free, physical capture of circulating tumor cell-clusters
por: Sarioglu, A. Fatih, et al.
Publicado: (2015)

Label-free enrichment of rare unconventional circulating neoplastic cells using a microfluidic dielectrophoretic sorting device
por: Montoya Mira, Jose, et al.
Publicado: (2021)

Gauging the Impact of Cancer Treatment Modalities on Circulating Tumor Cells (CTCs)
por: Mathias, Trevor J., et al.
Publicado: (2020)

The Mechanical Fingerprint of Circulating Tumor Cells (CTCs) in Breast Cancer Patients
por: Nel, Ivonne, et al.
Publicado: (2021)

Circulating Tumour Cells (CTCs) in NSCLC: From Prognosis to Therapy Design
por: Kejík, Zdeněk, et al.
Publicado: (2021)

Droplet Microfluidic Device for Chemoenzymatic Sensing
por: Yakimov, Anton S., et al.
Publicado: (2022)

Are Circulating Tumor Cells (CTCs) Ready for Clinical Use in Breast Cancer? An Overview of Completed and Ongoing Trials Using CTCs for Clinical Treatment Decisions
por: Schochter, Fabienne, et al.
Publicado: (2019)

Quantitative Study of Cell Invasion Process under Extracellular Stimulation of Cytokine in a Microfluidic Device
por: Lei, Kin Fong, et al.
Publicado: (2016)

Technical validation of a new microfluidic device for enrichment of CTCs from large volumes of blood by using buffy coats to mimic diagnostic leukapheresis products
por: Guglielmi, R., et al.
Publicado: (2020)

Dangerous Liaisons: Circulating Tumor Cells (CTCs) and Cancer-Associated Fibroblasts (CAFs)
por: Hurtado, Pablo, et al.
Publicado: (2020)

Biosensors for the Isolation and Detection of Circulating Tumor Cells (CTCs) in Point-of-Care Settings
por: Goldstein, Isaac, et al.
Publicado: (2023)

Circulating Tumour Cells as an Independent Prognostic Factor in Patients with Advanced Oesophageal Squamous Cell Carcinoma Undergoing Chemoradiotherapy
por: Su, Po-Jung, et al.
Publicado: (2016)

MiSelect R System: the validation of a new detection system of CTCs and their correlation with prognosis in non-metastatic CRC patients
por: Lin, Chun-Chi, et al.
Publicado: (2023)

A Microfluidic Single-Cell Cloning (SCC) Device for the Generation of Monoclonal Cells
por: Yeh, Chuan-Feng, et al.
Publicado: (2020)

Detection of circulating tumor cells (CTCs) in cerebrospinal fluid of a patient with HER2-overexpressing gastric cancer and single cell analysis of intra-patient heterogeneity of CTCs
por: Cho, Jang Ho, et al.
Publicado: (2019)

Expansion of CTCs from early stage lung cancer patients using a microfluidic co-culture model
por: Zhang, Zhuo, et al.
Publicado: (2014)

Deep Phenotypic Characterisation of CTCs by Combination of Microfluidic Isolation (IsoFlux) and Imaging Flow Cytometry (ImageStream)
por: Ruiz-Rodríguez, Antonio J., et al.
Publicado: (2021)

Liquid Biopsy in Lung Cancer: Clinical Applications of Circulating Biomarkers (CTCs and ctDNA)
por: Lim, Minji, et al.
Publicado: (2018)

The propensity of invasive circulating tumor cells (iCTCs) in metastatic progression and therapeutic responsiveness
por: Dong, Huan, et al.
Publicado: (2019)

CTC-Derived Models: A Window into the Seeding Capacity of Circulating Tumor Cells (CTCs)
por: Tayoun, Tala, et al.
Publicado: (2019)

Enhancing Prediction Performance by Add-On Combining Circulating Tumor Cell Count, CD45(neg) EpCAM(neg) Cell Count on Colorectal Cancer, Advance, and Metastasis
por: Chiu, Sherry Yueh-Hsia, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_sh5rsv7j9kd56621a7p1p11din