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The VSFASSQQ motif confers calcium sensitivity to the intracellular apyrase LALP70

BACKGROUND: Apyrases are divalent ion dependent tri- and dinucleotide phosphatases with different substrate specificity. The intracellular lysosomal apyrase LALP70 is also expressed as a splice variant (LALP70v) lacking a VSFASSQQ motif in the center of the molecule (aminoacids 287–294). However, th...

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Detalles Bibliográficos
Autores principales: Biederbick, Annette, Rösser, Ralf, Storre, Jörg, Elsässer, Hans-Peter
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC443525/
https://www.ncbi.nlm.nih.gov/pubmed/15200686
http://dx.doi.org/10.1186/1471-2091-5-8