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Delivery of microRNA-146a with polyethylenimine nanoparticles inhibits renal fibrosis in vivo

Renal fibrosis is the final common pathway leading to end-stage renal disease. Although microRNA (miR) was recently shown to be involved in the development of renal fibrosis, few studies have focused on the effects on renal fibrosis of exogenous miR delivered in an in vivo therapeutic setting. The s...

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Detalles Bibliográficos
Autores principales: Morishita, Yoshiyuki, Imai, Toshimi, Yoshizawa, Hiromichi, Watanabe, Minami, Ishibashi, Kenichi, Muto, Shigeaki, Nagata, Daisuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4435251/
https://www.ncbi.nlm.nih.gov/pubmed/25999712
http://dx.doi.org/10.2147/IJN.S82587