A Case of Persistent Helicobacter pylori Infection Occurring with Anti-IgE Immunosuppression

The increasingly widespread use of novel immunosuppressive drugs may lead to unexpected infectious complications. We report a case of persistent Helicobacter pylori (H. pylori) infection that failed to respond to antimicrobial therapy in a patient receiving omalizumab (Xolair™, Genentech USA Inc., S...

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Detalles Bibliográficos
Autores principales: Zandman, Daniel, Hahn, William, Moss, Steven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American College of Gastroenterology 2013
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4435255/
https://www.ncbi.nlm.nih.gov/pubmed/26157810
http://dx.doi.org/10.14309/crj.2013.8
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author Zandman, Daniel
Hahn, William
Moss, Steven
author_facet Zandman, Daniel
Hahn, William
Moss, Steven
author_sort Zandman, Daniel
collection PubMed
description The increasingly widespread use of novel immunosuppressive drugs may lead to unexpected infectious complications. We report a case of persistent Helicobacter pylori (H. pylori) infection that failed to respond to antimicrobial therapy in a patient receiving omalizumab (Xolair™, Genentech USA Inc., San Francisco, CA and Novartis Pharmaceuticals, Basel, Switzerland), an anti-IgE monoclonal antibody approved by the FDA for treatment of severe persistent asthma. To our knowledge, this is the first case report linking an immunosuppressive regimen containing anti-IgE biologic therapy to persistent H. pylori infection.
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spelling pubmed-44352552015-07-08 A Case of Persistent Helicobacter pylori Infection Occurring with Anti-IgE Immunosuppression Zandman, Daniel Hahn, William Moss, Steven ACG Case Rep J Case Report The increasingly widespread use of novel immunosuppressive drugs may lead to unexpected infectious complications. We report a case of persistent Helicobacter pylori (H. pylori) infection that failed to respond to antimicrobial therapy in a patient receiving omalizumab (Xolair™, Genentech USA Inc., San Francisco, CA and Novartis Pharmaceuticals, Basel, Switzerland), an anti-IgE monoclonal antibody approved by the FDA for treatment of severe persistent asthma. To our knowledge, this is the first case report linking an immunosuppressive regimen containing anti-IgE biologic therapy to persistent H. pylori infection. American College of Gastroenterology 2013-10-08 /pmc/articles/PMC4435255/ /pubmed/26157810 http://dx.doi.org/10.14309/crj.2013.8 Text en Copyright © Zandman et al. This is an open-access article. This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/3.0
spellingShingle Case Report
Zandman, Daniel
Hahn, William
Moss, Steven
A Case of Persistent Helicobacter pylori Infection Occurring with Anti-IgE Immunosuppression
title A Case of Persistent Helicobacter pylori Infection Occurring with Anti-IgE Immunosuppression
title_full A Case of Persistent Helicobacter pylori Infection Occurring with Anti-IgE Immunosuppression
title_fullStr A Case of Persistent Helicobacter pylori Infection Occurring with Anti-IgE Immunosuppression
title_full_unstemmed A Case of Persistent Helicobacter pylori Infection Occurring with Anti-IgE Immunosuppression
title_short A Case of Persistent Helicobacter pylori Infection Occurring with Anti-IgE Immunosuppression
title_sort case of persistent helicobacter pylori infection occurring with anti-ige immunosuppression
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4435255/
https://www.ncbi.nlm.nih.gov/pubmed/26157810
http://dx.doi.org/10.14309/crj.2013.8
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