Iron Pill–Induced Gastritis

Iron-deficiency anemia is a prevalent condition treated with iron supplementation. Iron pill–induced gastritis is an under-recognized, albeit serious potential complication of iron pill ingestion. This entity must be identified by healthcare providers who prescribe iron. We present a case of a 59-year-old male with iron deficiency anemia on ferrous sulfate tablets who underwent an upper endoscopy, during which a single superficial gastric ulceration in the body was noted. Biopsies revealed heavy iron deposition confirming the ulceration was a consequence of the iron tablets. Iron pill–induced gastritis causes corrosive mucosal injury similar to that caused by chemical burns.