Sarcoidosis Presenting as Necrotizing Sarcoid Granulomatosis of the Liver, Sclerosing Cholangitis, and Gastric Ulcer

Sarcoidosis is a multisystem granulomatous disease. The liver is affected in up to 50–90% of cases. Sarcoidosis typically presents as non-necrotizing epithelioid granuloma. The occurrence of non-infective necrotizing sarcoid granuloma (NSG) is infrequent, and the finding of NSG in the liver is rare....

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Detalles Bibliográficos
Autores principales: Momah, Njideka, Otesile, Adetola, Pawa, Rishi, Shedlofsky, Steve
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American College of Gastroenterology 2014
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4435308/
https://www.ncbi.nlm.nih.gov/pubmed/26157862
http://dx.doi.org/10.14309/crj.2014.38
Descripción
Sumario:Sarcoidosis is a multisystem granulomatous disease. The liver is affected in up to 50–90% of cases. Sarcoidosis typically presents as non-necrotizing epithelioid granuloma. The occurrence of non-infective necrotizing sarcoid granuloma (NSG) is infrequent, and the finding of NSG in the liver is rare. We report a case of NSG of the liver and lymph nodes, granulomatous gastric ulcer, and secondary cholangitis coexisting in a patient. We discuss the clinical features of the case and briefly review NSG. There is only 1 previously reported case of NSG of the liver in literature.

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