Sarcoidosis Presenting as Necrotizing Sarcoid Granulomatosis of the Liver, Sclerosing Cholangitis, and Gastric Ulcer

Sarcoidosis is a multisystem granulomatous disease. The liver is affected in up to 50–90% of cases. Sarcoidosis typically presents as non-necrotizing epithelioid granuloma. The occurrence of non-infective necrotizing sarcoid granuloma (NSG) is infrequent, and the finding of NSG in the liver is rare....

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Autores principales: Momah, Njideka, Otesile, Adetola, Pawa, Rishi, Shedlofsky, Steve
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American College of Gastroenterology 2014
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4435308/
https://www.ncbi.nlm.nih.gov/pubmed/26157862
http://dx.doi.org/10.14309/crj.2014.38
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author Momah, Njideka
Otesile, Adetola
Pawa, Rishi
Shedlofsky, Steve
author_facet Momah, Njideka
Otesile, Adetola
Pawa, Rishi
Shedlofsky, Steve
author_sort Momah, Njideka
collection PubMed
description Sarcoidosis is a multisystem granulomatous disease. The liver is affected in up to 50–90% of cases. Sarcoidosis typically presents as non-necrotizing epithelioid granuloma. The occurrence of non-infective necrotizing sarcoid granuloma (NSG) is infrequent, and the finding of NSG in the liver is rare. We report a case of NSG of the liver and lymph nodes, granulomatous gastric ulcer, and secondary cholangitis coexisting in a patient. We discuss the clinical features of the case and briefly review NSG. There is only 1 previously reported case of NSG of the liver in literature.
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spelling pubmed-44353082015-07-08 Sarcoidosis Presenting as Necrotizing Sarcoid Granulomatosis of the Liver, Sclerosing Cholangitis, and Gastric Ulcer Momah, Njideka Otesile, Adetola Pawa, Rishi Shedlofsky, Steve ACG Case Rep J Case Report Sarcoidosis is a multisystem granulomatous disease. The liver is affected in up to 50–90% of cases. Sarcoidosis typically presents as non-necrotizing epithelioid granuloma. The occurrence of non-infective necrotizing sarcoid granuloma (NSG) is infrequent, and the finding of NSG in the liver is rare. We report a case of NSG of the liver and lymph nodes, granulomatous gastric ulcer, and secondary cholangitis coexisting in a patient. We discuss the clinical features of the case and briefly review NSG. There is only 1 previously reported case of NSG of the liver in literature. American College of Gastroenterology 2014-04-04 /pmc/articles/PMC4435308/ /pubmed/26157862 http://dx.doi.org/10.14309/crj.2014.38 Text en Copyright © Momah et al. This is an open-access article. This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/4.0/
spellingShingle Case Report
Momah, Njideka
Otesile, Adetola
Pawa, Rishi
Shedlofsky, Steve
Sarcoidosis Presenting as Necrotizing Sarcoid Granulomatosis of the Liver, Sclerosing Cholangitis, and Gastric Ulcer
title Sarcoidosis Presenting as Necrotizing Sarcoid Granulomatosis of the Liver, Sclerosing Cholangitis, and Gastric Ulcer
title_full Sarcoidosis Presenting as Necrotizing Sarcoid Granulomatosis of the Liver, Sclerosing Cholangitis, and Gastric Ulcer
title_fullStr Sarcoidosis Presenting as Necrotizing Sarcoid Granulomatosis of the Liver, Sclerosing Cholangitis, and Gastric Ulcer
title_full_unstemmed Sarcoidosis Presenting as Necrotizing Sarcoid Granulomatosis of the Liver, Sclerosing Cholangitis, and Gastric Ulcer
title_short Sarcoidosis Presenting as Necrotizing Sarcoid Granulomatosis of the Liver, Sclerosing Cholangitis, and Gastric Ulcer
title_sort sarcoidosis presenting as necrotizing sarcoid granulomatosis of the liver, sclerosing cholangitis, and gastric ulcer
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4435308/
https://www.ncbi.nlm.nih.gov/pubmed/26157862
http://dx.doi.org/10.14309/crj.2014.38
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