Hematochezia Associated with Sevalamer-Induced Mucosal Injury

We present a case of a 61-year-old woman with end-stage renal disease (ESRD) who developed painless hematochezia following initiation of anticoagulation. Work-up revealed a large ulceration in the sigmoid colon, and histologic images revealed sevelamer crystals embedded in the colonic mucosa, consis...

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Detalles Bibliográficos
Autores principales: Chintamaneni, Preethi, Das, Rohit, Kuan, Shih-Fan, Kermanshahi, Taher R., Hashash, Jana G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American College of Gastroenterology 2014
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4435309/
https://www.ncbi.nlm.nih.gov/pubmed/26157856
http://dx.doi.org/10.14309/crj.2014.32
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author Chintamaneni, Preethi
Das, Rohit
Kuan, Shih-Fan
Kermanshahi, Taher R.
Hashash, Jana G.
author_facet Chintamaneni, Preethi
Das, Rohit
Kuan, Shih-Fan
Kermanshahi, Taher R.
Hashash, Jana G.
author_sort Chintamaneni, Preethi
collection PubMed
description We present a case of a 61-year-old woman with end-stage renal disease (ESRD) who developed painless hematochezia following initiation of anticoagulation. Work-up revealed a large ulceration in the sigmoid colon, and histologic images revealed sevelamer crystals embedded in the colonic mucosa, consistent with sevelamer crystal-mediated injury. This is a novel cause of gastrointestinal hemorrhage that has not previously been described in the literature. Physicians should be aware of the potential for sevelamer-induced injury.
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spelling pubmed-44353092015-07-08 Hematochezia Associated with Sevalamer-Induced Mucosal Injury Chintamaneni, Preethi Das, Rohit Kuan, Shih-Fan Kermanshahi, Taher R. Hashash, Jana G. ACG Case Rep J Case Report We present a case of a 61-year-old woman with end-stage renal disease (ESRD) who developed painless hematochezia following initiation of anticoagulation. Work-up revealed a large ulceration in the sigmoid colon, and histologic images revealed sevelamer crystals embedded in the colonic mucosa, consistent with sevelamer crystal-mediated injury. This is a novel cause of gastrointestinal hemorrhage that has not previously been described in the literature. Physicians should be aware of the potential for sevelamer-induced injury. American College of Gastroenterology 2014-04-04 /pmc/articles/PMC4435309/ /pubmed/26157856 http://dx.doi.org/10.14309/crj.2014.32 Text en Copyright © Chintamaneni et al. This is an open-access article. This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/4.0/
spellingShingle Case Report
Chintamaneni, Preethi
Das, Rohit
Kuan, Shih-Fan
Kermanshahi, Taher R.
Hashash, Jana G.
Hematochezia Associated with Sevalamer-Induced Mucosal Injury
title Hematochezia Associated with Sevalamer-Induced Mucosal Injury
title_full Hematochezia Associated with Sevalamer-Induced Mucosal Injury
title_fullStr Hematochezia Associated with Sevalamer-Induced Mucosal Injury
title_full_unstemmed Hematochezia Associated with Sevalamer-Induced Mucosal Injury
title_short Hematochezia Associated with Sevalamer-Induced Mucosal Injury
title_sort hematochezia associated with sevalamer-induced mucosal injury
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4435309/
https://www.ncbi.nlm.nih.gov/pubmed/26157856
http://dx.doi.org/10.14309/crj.2014.32
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AT kermanshahitaherr hematocheziaassociatedwithsevalamerinducedmucosalinjury
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