Aspirin-Induced Acute Liver Injury

Aspirin is thought to be a relatively safe drug in adults. The association of aspirin and Reye syndrome in children is well documented. We report a 41-year-old female with pericarditis who was treated with high-dose aspirin and developed subsequent acute liver injury. After discontinuation of aspiri...

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Detalles Bibliográficos
Autores principales: Laster, Janese, Satoskar, Rohit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American College of Gastroenterology 2014
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4435341/
https://www.ncbi.nlm.nih.gov/pubmed/26157904
http://dx.doi.org/10.14309/crj.2014.81
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author Laster, Janese
Satoskar, Rohit
author_facet Laster, Janese
Satoskar, Rohit
author_sort Laster, Janese
collection PubMed
description Aspirin is thought to be a relatively safe drug in adults. The association of aspirin and Reye syndrome in children is well documented. We report a 41-year-old female with pericarditis who was treated with high-dose aspirin and developed subsequent acute liver injury. After discontinuation of aspirin, liver enzyme elevation and right upper quadrant pain both resolved. We conclude that high-dose aspirin should be considered as a potentially hepatotoxic agent.
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spelling pubmed-44353412015-07-08 Aspirin-Induced Acute Liver Injury Laster, Janese Satoskar, Rohit ACG Case Rep J Case Report Aspirin is thought to be a relatively safe drug in adults. The association of aspirin and Reye syndrome in children is well documented. We report a 41-year-old female with pericarditis who was treated with high-dose aspirin and developed subsequent acute liver injury. After discontinuation of aspirin, liver enzyme elevation and right upper quadrant pain both resolved. We conclude that high-dose aspirin should be considered as a potentially hepatotoxic agent. American College of Gastroenterology 2014-10-10 /pmc/articles/PMC4435341/ /pubmed/26157904 http://dx.doi.org/10.14309/crj.2014.81 Text en Copyright © Laster et al. This is an open-access article. This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/4.0/
spellingShingle Case Report
Laster, Janese
Satoskar, Rohit
Aspirin-Induced Acute Liver Injury
title Aspirin-Induced Acute Liver Injury
title_full Aspirin-Induced Acute Liver Injury
title_fullStr Aspirin-Induced Acute Liver Injury
title_full_unstemmed Aspirin-Induced Acute Liver Injury
title_short Aspirin-Induced Acute Liver Injury
title_sort aspirin-induced acute liver injury
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4435341/
https://www.ncbi.nlm.nih.gov/pubmed/26157904
http://dx.doi.org/10.14309/crj.2014.81
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