Amiodarone-Induced Liver Injury and Cirrhosis

We present a case report of an 80-year-old woman with volume overload thought initially to be secondary to heart failure, but determined to be amiodarone-induced acute and chronic liver injury leading to submassive necrosis and bridging fibrosis consistent with early cirrhosis. Her histopathology wa...

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Detalles Bibliográficos
Autores principales: Buggey, Jonathan, Kappus, Matthew, Lagoo, Anand S., Brady, Carla W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American College of Gastroenterology 2015
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4435372/
https://www.ncbi.nlm.nih.gov/pubmed/26157932
http://dx.doi.org/10.14309/crj.2015.23
Descripción
Sumario:We present a case report of an 80-year-old woman with volume overload thought initially to be secondary to heart failure, but determined to be amiodarone-induced acute and chronic liver injury leading to submassive necrosis and bridging fibrosis consistent with early cirrhosis. Her histopathology was uniquely absent of steatosis and phospholipidosis, which are commonly seen in AIC.

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