Remission of Refractory Celiac Disease With Infliximab in a Pediatric Patient

Refractory celiac disease (RCD) is a rare but life-threatening complication of celiac disease (CD), and only 1 pediatric case has been reported. We report a case of a 14-year-old girl with CD presenting with persistent symptoms and positive tissue celiac-specific antibodies despite a gluten-free die...

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Autores principales: Rawal, Nidhi, Twaddell, William, Fasano, Alessio, Blanchard, Samra, Safta, Anca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American College of Gastroenterology 2015
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4435386/
https://www.ncbi.nlm.nih.gov/pubmed/26157934
http://dx.doi.org/10.14309/crj.2015.25
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author Rawal, Nidhi
Twaddell, William
Fasano, Alessio
Blanchard, Samra
Safta, Anca
author_facet Rawal, Nidhi
Twaddell, William
Fasano, Alessio
Blanchard, Samra
Safta, Anca
author_sort Rawal, Nidhi
collection PubMed
description Refractory celiac disease (RCD) is a rare but life-threatening complication of celiac disease (CD), and only 1 pediatric case has been reported. We report a case of a 14-year-old girl with CD presenting with persistent symptoms and positive tissue celiac-specific antibodies despite a gluten-free diet. Push enteroscopy showed jejunal scalloping and partial villous atrophy on histology. She was diagnosed with RCD and treated with infliximab with subsequent complete serological and histological remission.
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spelling pubmed-44353862015-07-08 Remission of Refractory Celiac Disease With Infliximab in a Pediatric Patient Rawal, Nidhi Twaddell, William Fasano, Alessio Blanchard, Samra Safta, Anca ACG Case Rep J Case Report Refractory celiac disease (RCD) is a rare but life-threatening complication of celiac disease (CD), and only 1 pediatric case has been reported. We report a case of a 14-year-old girl with CD presenting with persistent symptoms and positive tissue celiac-specific antibodies despite a gluten-free diet. Push enteroscopy showed jejunal scalloping and partial villous atrophy on histology. She was diagnosed with RCD and treated with infliximab with subsequent complete serological and histological remission. American College of Gastroenterology 2015-01-16 /pmc/articles/PMC4435386/ /pubmed/26157934 http://dx.doi.org/10.14309/crj.2015.25 Text en Copyright © Rawal et al. This is an open-access article. This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/4.0/
spellingShingle Case Report
Rawal, Nidhi
Twaddell, William
Fasano, Alessio
Blanchard, Samra
Safta, Anca
Remission of Refractory Celiac Disease With Infliximab in a Pediatric Patient
title Remission of Refractory Celiac Disease With Infliximab in a Pediatric Patient
title_full Remission of Refractory Celiac Disease With Infliximab in a Pediatric Patient
title_fullStr Remission of Refractory Celiac Disease With Infliximab in a Pediatric Patient
title_full_unstemmed Remission of Refractory Celiac Disease With Infliximab in a Pediatric Patient
title_short Remission of Refractory Celiac Disease With Infliximab in a Pediatric Patient
title_sort remission of refractory celiac disease with infliximab in a pediatric patient
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4435386/
https://www.ncbi.nlm.nih.gov/pubmed/26157934
http://dx.doi.org/10.14309/crj.2015.25
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