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pH-sensitive poly(lactide-co-glycolide) nanoparticle composite microcapsules for oral delivery of insulin

This study proposes a new concept of pH-sensitive poly(lactide-co-glycolide) (PLGA) nanoparticle composite microcapsules for oral delivery of insulin. Firstly, insulin–sodium oleate complex was prepared by the hydrophobic ion pairing method and then encapsulated into PLGA nanoparticles by the emulsi...

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Detalles Bibliográficos
Autores principales:	Sun, Shaoping, Liang, Na, Yamamoto, Hiromitsu, Kawashima, Yoshiaki, Cui, Fude, Yan, Pengfei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2015
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4435433/ https://www.ncbi.nlm.nih.gov/pubmed/25999713 http://dx.doi.org/10.2147/IJN.S81715

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