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Transgenic LRRK2(R1441G) rats–a model for Parkinson disease?

Parkinson disease (PD) is the most common movement disorder, characterized by the progressive degeneration of dopaminergic neurons in the substantia nigra. While the cause of this disease is largely unknown, a rare autosomal dominant familial form of PD is caused by a genetic mutation in the leucine...

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Detalles Bibliográficos
Autores principales: Shaikh, Komal T., Yang, Alvin, Youshin, Ekaterina, Schmid, Susanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4435452/
https://www.ncbi.nlm.nih.gov/pubmed/26020005
http://dx.doi.org/10.7717/peerj.945