Cargando…

Compulsory drug detention exposure is associated with not receiving antiretroviral treatment among people who inject drugs in Bangkok, Thailand: a cross-sectional study

BACKGROUND: Thailand has experienced a longstanding epidemic of HIV among people who inject drugs (PWID). However, antiretroviral treatment (ART) coverage among HIV-positive PWID has historically remained low. While ongoing drug law enforcement involving periodic police crackdowns is known to increa...

Descripción completa

Detalles Bibliográficos
Autores principales: Hayashi, Kanna, Ti, Lianping, Avihingsanon, Anchalee, Kaplan, Karyn, Suwannawong, Paisan, Wood, Evan, Montaner, Julio S G, Kerr, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4435625/
https://www.ncbi.nlm.nih.gov/pubmed/25943881
http://dx.doi.org/10.1186/s13011-015-0013-6
_version_ 1782371945196552192
author Hayashi, Kanna
Ti, Lianping
Avihingsanon, Anchalee
Kaplan, Karyn
Suwannawong, Paisan
Wood, Evan
Montaner, Julio S G
Kerr, Thomas
author_facet Hayashi, Kanna
Ti, Lianping
Avihingsanon, Anchalee
Kaplan, Karyn
Suwannawong, Paisan
Wood, Evan
Montaner, Julio S G
Kerr, Thomas
author_sort Hayashi, Kanna
collection PubMed
description BACKGROUND: Thailand has experienced a longstanding epidemic of HIV among people who inject drugs (PWID). However, antiretroviral treatment (ART) coverage among HIV-positive PWID has historically remained low. While ongoing drug law enforcement involving periodic police crackdowns is known to increase the risk of HIV transmission among Thai PWID, the impact of such drug policy approaches on the ART uptake has been understudied. Therefore, we sought to identify factors associated with not receiving ART among HIV-positive PWID in Bangkok, Thailand, with a focus on factors pertaining to drug law enforcement. METHODS: Data were collected from a community-recruited sample of HIV-positive PWID in Bangkok who participated in the Mitsampan Community Research Project between June 2009 and October 2011. We identified factors associated with not receiving ART at the time of interview using multivariate logistic regression. RESULTS: In total, 128 HIV-positive PWID participated in this study, with 58 (45.3%) reporting not receiving ART at the time of interview. In multivariate analyses, completing less than secondary education (adjusted odds ratio [AOR]: 3.32 ; 95% confidence interval [CI]: 1.48 – 7.45), daily midazolam injection (AOR: 3.22, 95% CI: 1.45 – 7.15) and exposure to compulsory drug detention (AOR: 3.36, 95% CI: 1.01 – 11.21) were independently and positively associated with not receiving ART. Accessing peer-based healthcare information or support services was independently and positively associated with receiving ART (AOR: 0.21, 95% CI: 0.05 – 0.84). CONCLUSIONS: Approximately half of our study group of HIV-positive PWID reported not receiving ART at the time of interview. Daily midazolam injectors, those with lower education attainment, and individuals who had been in compulsory drug detention were more likely to be non-recipients of ART whereas those who accessed peer-based healthcare-related services were more likely to receive ART. These findings suggest a potentially adverse impact of compulsory drug detention and highlight the need to expand interventions to facilitate access to ART among HIV-positive PWID in this setting.
format Online
Article
Text
id pubmed-4435625
institution National Center for Biotechnology Information
language English
publishDate 2015
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-44356252015-05-19 Compulsory drug detention exposure is associated with not receiving antiretroviral treatment among people who inject drugs in Bangkok, Thailand: a cross-sectional study Hayashi, Kanna Ti, Lianping Avihingsanon, Anchalee Kaplan, Karyn Suwannawong, Paisan Wood, Evan Montaner, Julio S G Kerr, Thomas Subst Abuse Treat Prev Policy Research BACKGROUND: Thailand has experienced a longstanding epidemic of HIV among people who inject drugs (PWID). However, antiretroviral treatment (ART) coverage among HIV-positive PWID has historically remained low. While ongoing drug law enforcement involving periodic police crackdowns is known to increase the risk of HIV transmission among Thai PWID, the impact of such drug policy approaches on the ART uptake has been understudied. Therefore, we sought to identify factors associated with not receiving ART among HIV-positive PWID in Bangkok, Thailand, with a focus on factors pertaining to drug law enforcement. METHODS: Data were collected from a community-recruited sample of HIV-positive PWID in Bangkok who participated in the Mitsampan Community Research Project between June 2009 and October 2011. We identified factors associated with not receiving ART at the time of interview using multivariate logistic regression. RESULTS: In total, 128 HIV-positive PWID participated in this study, with 58 (45.3%) reporting not receiving ART at the time of interview. In multivariate analyses, completing less than secondary education (adjusted odds ratio [AOR]: 3.32 ; 95% confidence interval [CI]: 1.48 – 7.45), daily midazolam injection (AOR: 3.22, 95% CI: 1.45 – 7.15) and exposure to compulsory drug detention (AOR: 3.36, 95% CI: 1.01 – 11.21) were independently and positively associated with not receiving ART. Accessing peer-based healthcare information or support services was independently and positively associated with receiving ART (AOR: 0.21, 95% CI: 0.05 – 0.84). CONCLUSIONS: Approximately half of our study group of HIV-positive PWID reported not receiving ART at the time of interview. Daily midazolam injectors, those with lower education attainment, and individuals who had been in compulsory drug detention were more likely to be non-recipients of ART whereas those who accessed peer-based healthcare-related services were more likely to receive ART. These findings suggest a potentially adverse impact of compulsory drug detention and highlight the need to expand interventions to facilitate access to ART among HIV-positive PWID in this setting. BioMed Central 2015-05-06 /pmc/articles/PMC4435625/ /pubmed/25943881 http://dx.doi.org/10.1186/s13011-015-0013-6 Text en © Hayashi et al.; licensee BioMed Central. 2015 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research
Hayashi, Kanna
Ti, Lianping
Avihingsanon, Anchalee
Kaplan, Karyn
Suwannawong, Paisan
Wood, Evan
Montaner, Julio S G
Kerr, Thomas
Compulsory drug detention exposure is associated with not receiving antiretroviral treatment among people who inject drugs in Bangkok, Thailand: a cross-sectional study
title Compulsory drug detention exposure is associated with not receiving antiretroviral treatment among people who inject drugs in Bangkok, Thailand: a cross-sectional study
title_full Compulsory drug detention exposure is associated with not receiving antiretroviral treatment among people who inject drugs in Bangkok, Thailand: a cross-sectional study
title_fullStr Compulsory drug detention exposure is associated with not receiving antiretroviral treatment among people who inject drugs in Bangkok, Thailand: a cross-sectional study
title_full_unstemmed Compulsory drug detention exposure is associated with not receiving antiretroviral treatment among people who inject drugs in Bangkok, Thailand: a cross-sectional study
title_short Compulsory drug detention exposure is associated with not receiving antiretroviral treatment among people who inject drugs in Bangkok, Thailand: a cross-sectional study
title_sort compulsory drug detention exposure is associated with not receiving antiretroviral treatment among people who inject drugs in bangkok, thailand: a cross-sectional study
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4435625/
https://www.ncbi.nlm.nih.gov/pubmed/25943881
http://dx.doi.org/10.1186/s13011-015-0013-6
work_keys_str_mv AT hayashikanna compulsorydrugdetentionexposureisassociatedwithnotreceivingantiretroviraltreatmentamongpeoplewhoinjectdrugsinbangkokthailandacrosssectionalstudy
AT tilianping compulsorydrugdetentionexposureisassociatedwithnotreceivingantiretroviraltreatmentamongpeoplewhoinjectdrugsinbangkokthailandacrosssectionalstudy
AT avihingsanonanchalee compulsorydrugdetentionexposureisassociatedwithnotreceivingantiretroviraltreatmentamongpeoplewhoinjectdrugsinbangkokthailandacrosssectionalstudy
AT kaplankaryn compulsorydrugdetentionexposureisassociatedwithnotreceivingantiretroviraltreatmentamongpeoplewhoinjectdrugsinbangkokthailandacrosssectionalstudy
AT suwannawongpaisan compulsorydrugdetentionexposureisassociatedwithnotreceivingantiretroviraltreatmentamongpeoplewhoinjectdrugsinbangkokthailandacrosssectionalstudy
AT woodevan compulsorydrugdetentionexposureisassociatedwithnotreceivingantiretroviraltreatmentamongpeoplewhoinjectdrugsinbangkokthailandacrosssectionalstudy
AT montanerjuliosg compulsorydrugdetentionexposureisassociatedwithnotreceivingantiretroviraltreatmentamongpeoplewhoinjectdrugsinbangkokthailandacrosssectionalstudy
AT kerrthomas compulsorydrugdetentionexposureisassociatedwithnotreceivingantiretroviraltreatmentamongpeoplewhoinjectdrugsinbangkokthailandacrosssectionalstudy