The Legionella Kinase LegK2 Targets the ARP2/3 Complex To Inhibit Actin Nucleation on Phagosomes and Allow Bacterial Evasion of the Late Endocytic Pathway

Legionella pneumophila, the etiological agent of legionellosis, replicates within phagocytic cells. Crucial to biogenesis of the replicative vacuole is the Dot/Icm type 4 secretion system, which translocates a large number of effectors into the host cell cytosol. Among them is LegK2, a protein kinas...

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Detalles Bibliográficos
Autores principales: Michard, Céline, Sperandio, Daniel, Baïlo, Nathalie, Pizarro-Cerdá, Javier, LeClaire, Lawrence, Chadeau-Argaud, Elise, Pombo-Grégoire, Isabel, Hervet, Eva, Vianney, Anne, Gilbert, Christophe, Faure, Mathias, Cossart, Pascale, Doublet, Patricia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4436068/
https://www.ncbi.nlm.nih.gov/pubmed/25944859
http://dx.doi.org/10.1128/mBio.00354-15

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