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Optimisation of immunofluorescence methods to determine MCT1 and MCT4 expression in circulating tumour cells

BACKGROUND: The monocarboxylate transporter-1 (MCT1) represents a novel target in rational anticancer drug design while AZD3965 was developed as an inhibitor of this transporter and is undergoing Phase I clinical trials (http://www.clinicaltrials.gov/show/NCT01791595). We describe the optimisation o...

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Detalles Bibliográficos
Autores principales:	Kershaw, Stephen, Cummings, Jeffrey, Morris, Karen, Tugwood, Jonathan, Dive, Caroline
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Technical Advance
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4436118/ https://www.ncbi.nlm.nih.gov/pubmed/25957999 http://dx.doi.org/10.1186/s12885-015-1382-y

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