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Germline TP53 mutational spectrum in French Canadians with breast cancer
BACKGROUND: Specific germline mutations in the hereditary breast-ovarian cancer susceptibility (HBC/HBOC) genes, BRCA1, BRCA2 and PALB2, have been shown to recur in French Canadians of Quebec, Canada, and this has been attributed to common ancestors. Germline TP53 mutation carriers are known to segr...
Autores principales: | Arcand, Suzanna L, Akbari, Mohammed R, Mes-Masson, Anne-Marie, Provencher, Diane, Foulkes, William D, Narod, Steven A, Tonin, Patricia N |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4436120/ https://www.ncbi.nlm.nih.gov/pubmed/25925845 http://dx.doi.org/10.1186/s12881-015-0169-y |
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