A Prosaposin-Derived Peptide Alleviates Kainic Acid-Induced Brain Injury

Four sphingolipid activator proteins (i.e., saposins A–D) are synthesized from a single precursor protein, prosaposin (PS), which exerts exogenous neurotrophic effects in vivo and in vitro. Kainic acid (KA) injection in rodents is a good model in which to study neurotrophic factor elevation; PS and...

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Detalles Bibliográficos
Autores principales: Nabeka, Hiroaki, Shimokawa, Tetsuya, Doihara, Takuya, Saito, Shouichiro, Wakisaka, Hiroyuki, Hamada, Fumihiko, Kobayashi, Naoto, Matsuda, Seiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4436272/
https://www.ncbi.nlm.nih.gov/pubmed/25993033
http://dx.doi.org/10.1371/journal.pone.0126856

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4436272/
https://www.ncbi.nlm.nih.gov/pubmed/25993033
http://dx.doi.org/10.1371/journal.pone.0126856

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