Fas Signaling Promotes Gastric Cancer Metastasis through STAT3-Dependent Upregulation of Fascin

BACKGROUND: Fas signaling-activated signal transducers and activators of transcription 3 (STAT3) is required for Fascin upregulation. As an actin-bundling protein, Fascin can mediate gastric cancer (GC) cell migration. METHODS: Gastric cancer AGS cells were treated with anti-Fas (5 μg/ml) for 2 h, i...

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Detalles Bibliográficos
Autores principales: Yang, Yunshan, Zhao, Qiyu, Cai, Zhijian, Cheng, Guoping, Chen, Ming, Wang, Jiaoli, Zhong, Haijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4436300/
https://www.ncbi.nlm.nih.gov/pubmed/25992623
http://dx.doi.org/10.1371/journal.pone.0125132

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