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Construction of a Catsper1 DNA Vaccine and Its Antifertility Effect on Male Mice

Cation channel of sperm 1 (CATSPER1) is a unique sperm cation channel protein, and essential for sperm function and male fertility. CATSPER1 exclusively expresses in meiotic and postmeiotic spermatogenic cells, thus belongs to the spermatogenesis-specific antigen that escape central tolerance. We ha...

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Detalles Bibliográficos
Autores principales: Yu, Qiong, Mei, Xiao-Qin, Ding, Xiao-Fang, Dong, Ting-Ting, Dong, Wei-Wei, Li, Hong-Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4436331/
https://www.ncbi.nlm.nih.gov/pubmed/25993432
http://dx.doi.org/10.1371/journal.pone.0127508