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Long-Term Over-Expression of Neuropeptide Y in Hypothalamic Paraventricular Nucleus Contributes to Adipose Tissue Insulin Resistance Partly via the Y5 Receptor
Intracerebroventricular injection and overexpression of Neuropeptide Y (NPY) in the paraventricular nucleus (PVN) has been shown to induce obesity and glucose metabolism disorder in rodents; however, the underlying mechanisms are still unclear. The aim of this study was to investigate the mechanism...
Autores principales: | Long, Min, Zhou, Jiyin, Li, Dandan, Zheng, Lu, Xu, Zihui, Zhou, Shiwen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4436377/ https://www.ncbi.nlm.nih.gov/pubmed/25993471 http://dx.doi.org/10.1371/journal.pone.0126714 |
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