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TGF-Beta Blockade Increases Renal Inflammation Caused by the C-Terminal Module of the CCN2
The CCN family member 2 (CCN2, also known as connective tissue growth factor) may behave as a risk biomarker and a potential therapeutic target for renal disease. CCN2 participates in the regulation of inflammation and fibrosis. TGF-β is considered the main fibrogenic cytokine; however, in some path...
Autores principales: | Rodrigues-Díez, Raquel, Rayego-Mateos, Sandra, Orejudo, Macarena, Aroeira, Luiz Stark, Selgas, Rafael, Ortiz, Alberto, Egido, Jesús, Ruiz-Ortega, Marta |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4436472/ https://www.ncbi.nlm.nih.gov/pubmed/26074680 http://dx.doi.org/10.1155/2015/506041 |
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