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Enriched transcription factor signatures in triple negative breast cancer indicates possible targeted therapies with existing drugs

PURPOSE: Triple negative (TN) breast cancers which lack expression of the estrogen (ER), progesterone (PR), and human epidermal growth factor 2 (HER2) receptors convey a poor prognosis due in part to a lack of targeted therapies. METHODS: To identify viable targets for the treatment of TN disease, w...

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Detalles Bibliográficos
Autores principales:	Willis, Scooter, De, Pradip, Dey, Nandini, Long, Bradley, Young, Brandon, Sparano, Joseph A., Wang, Victoria, Davidson, Nancy E., Leyland-Jones, Brian R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4436509/ https://www.ncbi.nlm.nih.gov/pubmed/26005638 http://dx.doi.org/10.1016/j.mgene.2015.04.002

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