Exosomes Secreted from CXCR4 Overexpressing Mesenchymal Stem Cells Promote Cardioprotection via Akt Signaling Pathway following Myocardial Infarction

Background and Objective. Exosomes secreted from mesenchymal stem cells (MSC) have demonstrated cardioprotective effects. This study examined the role of exosomes derived from MSC overexpressing CXCR4 for recovery of cardiac functions after myocardial infarction (MI). Methods. In vitro, exosomes fro...

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Detalles Bibliográficos
Autores principales: Kang, Kai, Ma, Ruilian, Cai, Wenfeng, Huang, Wei, Paul, Christian, Liang, Jialiang, Wang, Yuhua, Zhao, Tiejun, Kim, Ha Won, Xu, Meifeng, Millard, Ronald W., Wen, Zhili, Wang, Yigang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4436515/
https://www.ncbi.nlm.nih.gov/pubmed/26074976
http://dx.doi.org/10.1155/2015/659890

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