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Genetic and structural analysis of the essential fission yeast RNA polymerase II CTD phosphatase Fcp1

Protein phosphatases regulate mRNA synthesis and processing by remodeling the carboxy-terminal domain (CTD) of RNA polymerase II (Pol2) to dynamically inscribe a Pol2 CTD code. Fission yeast Fcp1 (SpFcp1) is an essential 723-amino acid CTD phosphatase that preferentially hydrolyzes Ser2-PO(4) of the...

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Detalles Bibliográficos
Autores principales:	Schwer, Beate, Ghosh, Agnidipta, Sanchez, Ana M., Lima, Christopher D., Shuman, Stewart
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2015
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4436666/ https://www.ncbi.nlm.nih.gov/pubmed/25883047 http://dx.doi.org/10.1261/rna.050286.115

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