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Extracellular association of APP and tau fibrils induces intracellular aggregate formation of tau
Alzheimer’s disease (AD) is characterized by extracellular amyloid β (Aβ) deposition and intracellular tau aggregation. Many studies have indicated some association between these processes, but it remains unknown how the two pathologies are linked. In this study, we investigated whether expression o...
Autores principales: | Takahashi, Muneaki, Miyata, Haruka, Kametani, Fuyuki, Nonaka, Takashi, Akiyama, Haruhiko, Hisanaga, Shin-ichi, Hasegawa, Masato |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4436700/ https://www.ncbi.nlm.nih.gov/pubmed/25869641 http://dx.doi.org/10.1007/s00401-015-1415-2 |
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