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Extracellular association of APP and tau fibrils induces intracellular aggregate formation of tau

Alzheimer’s disease (AD) is characterized by extracellular amyloid β (Aβ) deposition and intracellular tau aggregation. Many studies have indicated some association between these processes, but it remains unknown how the two pathologies are linked. In this study, we investigated whether expression o...

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Detalles Bibliográficos
Autores principales: Takahashi, Muneaki, Miyata, Haruka, Kametani, Fuyuki, Nonaka, Takashi, Akiyama, Haruhiko, Hisanaga, Shin-ichi, Hasegawa, Masato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4436700/
https://www.ncbi.nlm.nih.gov/pubmed/25869641
http://dx.doi.org/10.1007/s00401-015-1415-2

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