Homer3 regulates the establishment of neutrophil polarity

Most chemoattractants rely on activation of the heterotrimeric G-protein Gαi to regulate directional cell migration, but few links from Gαi to chemotactic effectors are known. Through affinity chromatography using primary neutrophil lysate, we identify Homer3 as a novel Gαi2-binding protein. RNA int...

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Detalles Bibliográficos
Autores principales: Wu, Julie, Pipathsouk, Anne, Keizer-Gunnink, A., Fusetti, F., Alkema, W., Liu, Shanshan, Altschuler, Steven, Wu, Lani, Kortholt, Arjan, Weiner, Orion D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2015
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4436775/
https://www.ncbi.nlm.nih.gov/pubmed/25739453
http://dx.doi.org/10.1091/mbc.E14-07-1197

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4436775/
https://www.ncbi.nlm.nih.gov/pubmed/25739453
http://dx.doi.org/10.1091/mbc.E14-07-1197

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