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A novel function for the Caenorhabditis elegans torsin OOC-5 in nucleoporin localization and nuclear import

Torsin proteins are AAA+ ATPases that localize to the endoplasmic reticular/nuclear envelope (ER/NE) lumen. A mutation that markedly impairs torsinA function causes the CNS disorder DYT1 dystonia. Abnormalities of NE membranes have been linked to torsinA loss of function and the pathogenesis of DYT1...

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Detalles Bibliográficos
Autores principales:	VanGompel, Michael J. W., Nguyen, Ken C. Q., Hall, David H., Dauer, William T., Rose, Lesilee S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2015
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4436785/ https://www.ncbi.nlm.nih.gov/pubmed/25739455 http://dx.doi.org/10.1091/mbc.E14-07-1239

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